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#stats[hidden]{display:none}

.program-context{background:#f8f9fa;border-left:3px solid #0d6efd;border-radius:5px;padding:20px 23px;margin:24px 0}.program-context p{font-size:15px;line-height:1.85;color:#343a40;margin:0 0 14px}.program-context p:last-child{margin-bottom:0}

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.clinical-filter-grid label{min-width:0}.clinical-filter-grid select{min-width:0;max-width:100%}

:root{--teal:#176c94;--ink:#20252b}body{background:#fafafa;color:#20252b}header{background:#152b3a;border:0;box-shadow:0 1px 4px #0002}header .site-header-inner{max-width:1280px}header a,header summary,.brand12 small{color:#fff!important}.brand12 strong{font-size:27px}.brand12 small{font-size:10px}.institution-logo{background:white;border-radius:3px;padding:4px;width:104px;height:86px;object-fit:contain}.site-navigation{gap:19px}main{max-width:1200px;margin:auto;padding:34px 26px}h1{font-size:32px;color:#182e3c}h2{font-size:24px}h3{font-size:18px}.m14-heading{max-width:850px;padding:5px 0 25px}.m14-heading h1{font-size:48px;margin:12px 0 4px}.m14-heading h2{margin:0 0 20px;font-size:25px}.m14-heading p{font-size:17px;line-height:1.7}#home-search14{max-width:640px;margin-top:25px}#home-search14 label{font-weight:600;display:block;margin-bottom:7px}#home-search14>div{display:flex;gap:8px}#home-query14{flex:1;min-width:0;font-size:16px;padding:12px}.m14-stats{display:grid;grid-template-columns:repeat(4,1fr);border-top:1px solid #ccd3d8;border-left:1px solid #ccd3d8;margin:23px 0 15px}.m14-stat{padding:22px 19px;border-right:1px solid #ccd3d8;border-bottom:1px solid #ccd3d8;background:white}.m14-stat strong{font-size:32px;display:block;color:#176c94;line-height:1.3}.m14-stat span{display:block;margin-top:5px;font-weight:600}.m14-stat small{display:block;color:#687581;margin-top:7px;line-height:1.5}.m14-browsers{display:grid;grid-template-columns:repeat(2,1fr);gap:15px;margin:20px 0 30px}.m14-browsers a{padding:20px 24px;background:#fff;border:1px solid #ccd3d8;text-decoration:none;color:#20252b}.m14-browsers h3{color:#176c94;margin:0 0 8px}.m14-browsers p{margin:0}.m14-bottom{display:grid;grid-template-columns:1fr 1fr;gap:35px;border-top:1px solid #ccd3d8;padding:15px 0 30px}.m14-reference{border-top:1px solid #ccd3d8;padding:20px 0;color:#55616a}.m14-chart{margin:25px 0;padding:25px;background:#fff;border:1px solid #ccd3d8}.m14-bar{display:grid;grid-template-columns:235px 1fr 65px;align-items:center;gap:12px;margin:10px 0;font-size:13px}.m14-bar>div{display:flex;height:21px;background:#f3f5f7}.m14-bar i{background:#176c94}.m14-bar b{background:#6baf75}.m14-legend{display:flex;gap:22px;font-size:13px;margin-bottom:18px}.m14-legend span:first-child{color:#176c94}.m14-legend span:last-child{color:#498b53}.dropdown-links a{color:#20252b!important}.sub{line-height:1.65}.card{box-shadow:none;border-radius:2px}footer{font-size:12px}@media(max-width:800px){.m14-stats{grid-template-columns:repeat(2,1fr)}.m14-bar{grid-template-columns:140px 1fr 40px}.m14-bottom,.m14-browsers{grid-template-columns:1fr}.site-navigation{gap:10px;flex-wrap:wrap}main{padding:20px 14px}.brand12 small{display:none}.m14-heading h2{font-size:21px}}@media(max-width:450px){.m14-stats{grid-template-columns:1fr 1fr}.m14-stat{padding:16px 12px}.m14-stat strong{font-size:25px}.m14-bar{grid-template-columns:105px 1fr 32px;font-size:11px}}

header .brand12 strong{color:#fff}header a[aria-label]{text-decoration:none}header .brand12 small{text-decoration:none}
.overview-plots17{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:18px;margin:22px 0 10px}.overview-panel17{border:1px solid #ccd3d8;background:#fff;padding:20px 12px 3px;min-width:0}.overview-panel17 h3{margin:0 8px 10px;font-size:18px;color:#183748}.overview-panel17>p{margin:0 8px;min-height:88px;font-size:13px;line-height:1.6;color:#62717c}.overview-panel17 svg{display:block;width:100%;height:auto;font-family:Arial,sans-serif}@media(max-width:900px){.overview-plots17{grid-template-columns:1fr}.overview-panel17>p{min-height:0}.overview-panel17 svg{max-width:600px;margin:auto}}

.m14-axis19{margin-bottom:16px}.m14-axis19>div{position:relative;height:22px;background:transparent;border-bottom:1px solid #b7c2c9}.m14-axis19>div>span{position:absolute;bottom:3px;transform:translateX(-50%);font-size:11px;color:#62717c;font-variant-numeric:tabular-nums}.m14-axis19>div>span:first-child{transform:none}.m14-axis19>div>span:last-child{transform:translateX(-100%)}

.contact-grid19{display:grid;grid-template-columns:minmax(0,1fr) minmax(0,1.3fr);gap:24px;margin-top:24px}.contact-grid19 .card{margin:0;min-width:0}.contact-grid19 h2{margin-top:0}#contact-form19{display:grid;gap:10px}#contact-form19 label{font-weight:600;margin-top:6px}#contact-form19 input,#contact-form19 textarea{width:100%;min-width:0;box-sizing:border-box;font:inherit;padding:12px;border:1px solid #c6d0d8;border-radius:6px;background:#fff;color:var(--ink)}#contact-form19 textarea{resize:vertical}#contact-form19 button{justify-self:start}#contact-form19 .subnote{margin:4px 0 10px}.contact-email19{overflow-wrap:anywhere}#contact-status19:empty{display:none}@media(max-width:750px){.contact-grid19{grid-template-columns:1fr}}

.home-context19{margin-top:24px}.home-context19 h2{margin-top:0}.home-context19 p{font-size:15px;line-height:1.8;max-width:100ch}.home-context19 p:last-child{margin-bottom:0}

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/* Slightly slimmer bars; numeric scales and lengths are unchanged. */
.m14-bar:not(.m14-axis19)>div{height:17px}.bartrack{height:10px}

.updates-page21{max-width:920px}.updates-page21 .card h2{margin-top:0}.updates-page21 .card p{max-width:78ch}

.help-layout22{display:grid;grid-template-columns:225px minmax(0,1fr);gap:26px;align-items:start}.help-nav22{position:sticky;top:20px;background:#fff;border:1px solid #dce4e8;border-radius:8px;padding:20px}.help-nav22 h2{font-size:16px;margin:0 0 12px}.help-nav22 nav{display:block;margin:0;border:0;overflow:visible}.help-nav22 a{display:block;font-size:13px;line-height:1.5;padding:5px 0;text-decoration:none;color:#176c94}.help-nav22 a:hover{text-decoration:underline}.help-body22{min-width:0}.help-section22{background:#fff;border:1px solid #dce4e8;border-radius:8px;padding:26px;margin-bottom:20px;line-height:1.8;scroll-margin-top:20px}.help-section22 h1{margin-top:0}.help-section22 h2{margin-top:0;font-size:22px}.help-section22 .subtitle{font-size:24px;font-weight:500}.help-section22 .section-link{font-size:13px;font-weight:600}.help-section22 .definition{border-top:1px solid #e8edf0;padding:14px 0}.help-section22 .definition:first-child{border:0}.help-section22 dt{font-weight:700;color:#24465a}.help-section22 dd{margin:4px 0 0}.help-section22 p:last-child{margin-bottom:0}@media(max-width:850px){.help-layout22{grid-template-columns:1fr}.help-nav22{position:static}.help-nav22 nav{display:grid;grid-template-columns:1fr 1fr;gap:0 16px}}@media(max-width:480px){.help-nav22 nav{grid-template-columns:1fr}.help-section22{padding:20px}}

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/* Shared spacing and column geometry across record and browser views. */
:root{--frame-gap18:20px;--frame-padding18:24px;--frame-radius18:8px}
#workspace,#workspace>*{min-width:0}
.card,.recordhead,.filters,.chartcard,.m14-chart,.panelpreview{box-sizing:border-box;max-width:100%;border:1px solid var(--line);border-radius:var(--frame-radius18);padding:var(--frame-padding18);margin:0 0 var(--frame-gap18)}
.card+.card{margin-top:0}
.info-grid,.figuregrid,.coverage-grid,.evidence-grid{gap:var(--frame-gap18);align-items:stretch;grid-template-columns:repeat(2,minmax(0,1fr));margin-block:var(--frame-gap18)}
.info-grid>*,.figuregrid>*,.coverage-grid>*,.evidence-grid>*{min-width:0}
.info-grid>.card,.figuregrid>.card,.coverage-grid>.card,.evidence-grid>.card{margin:0;height:100%}
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.coverage-grid,.evidence-grid{grid-template-columns:repeat(3,minmax(0,1fr))}
.metricgrid{grid-template-columns:repeat(4,minmax(0,1fr));gap:16px;margin:var(--frame-gap18) 0;align-items:stretch}
.metricgrid>div{box-sizing:border-box;min-width:0;min-height:96px;padding:16px;border:1px solid var(--line);border-radius:6px;overflow-wrap:anywhere}
.metricgrid strong{line-height:1.3;font-variant-numeric:tabular-nums}
.metricgrid span{display:block;margin-top:6px;line-height:1.5}
.m14-stats{grid-template-columns:repeat(auto-fit,minmax(min(100%,220px),1fr));margin-block:var(--frame-gap18)}
.overview-plots17,.m14-browsers{gap:var(--frame-gap18)}
.overview-panel17,.m14-browsers>a{border-color:var(--line);border-radius:var(--frame-radius18);min-width:0}
.overview-panel17{height:100%}
.card>h3:first-child,.card>h2:first-child{margin-top:0}
.kv{grid-template-columns:minmax(105px,35%) minmax(0,1fr);gap:10px 16px}
.kv dt,.kv dd{min-width:0;overflow-wrap:anywhere}
.tablewrap{box-sizing:border-box;width:100%;max-width:100%;min-width:0;overflow-x:auto;border:1px solid var(--line);border-radius:var(--frame-radius18);background:#fff}
.card>.tablewrap{margin-top:16px}
.tablewrap+.tablewrap{margin-top:var(--frame-gap18)}
.tablewrap table{width:100%;margin:0;border-collapse:collapse;font-variant-numeric:tabular-nums}
.tablewrap th,.tablewrap td,.tablewrap .compact th,.tablewrap .compact td{box-sizing:border-box;padding:14px 16px;vertical-align:top;line-height:1.5;overflow-wrap:anywhere}
.tablewrap th{white-space:normal}
.tablewrap caption{padding:14px 16px;text-align:left;line-height:1.5}
.tablewrap tbody tr:last-child td{border-bottom:0}
.frequency-table18{table-layout:fixed;min-width:620px}
.frequency-label18{width:46%}.frequency-value18{width:32%}.frequency-result18{width:22%}
.frequency-table18 th:nth-child(n+2),.frequency-table18 td:nth-child(n+2){text-align:right;white-space:nowrap}
.omim-table18{table-layout:fixed;min-width:600px}
.gene-variants-table18{table-layout:fixed;min-width:720px}
.gene-variants-table18 th:nth-child(n+3),.gene-variants-table18 td:nth-child(n+3){text-align:right}
.gene-browser-table18,.panel-table18{table-layout:fixed;min-width:700px}
.gene-browser-table18 th:nth-child(n+2),.gene-browser-table18 td:nth-child(n+2),.panel-table18 th:nth-child(n+3),.panel-table18 td:nth-child(n+3){text-align:right}
.variant-browser-table18{table-layout:fixed;min-width:1520px}
.comparison-table18{table-layout:fixed;min-width:1565px}
.variant-browser-table18 td.variant,.comparison-table18 td.variant{max-width:none}
.comparison-table18 th:nth-child(n+3):nth-child(-n+8),.comparison-table18 td:nth-child(n+3):nth-child(-n+8){text-align:right}
.variant-browser-table18 th:nth-child(4),.variant-browser-table18 td:nth-child(4),.variant-browser-table18 th:nth-child(5),.variant-browser-table18 td:nth-child(5),.variant-browser-table18 th:nth-child(n+7),.variant-browser-table18 td:nth-child(n+7){text-align:right}
.filtergrid,.clinical-filter-grid{gap:16px;align-items:end}
.filtergrid label,.clinical-filter-grid label{min-width:0;line-height:1.5}
.filtergrid input,.filtergrid select,.clinical-filter-grid select{min-height:42px;box-sizing:border-box;max-width:100%;margin-top:6px}
.barrow{grid-template-columns:minmax(190px,30%) minmax(0,1fr) 100px;gap:16px}
.barrow>span:last-child{text-align:right;font-variant-numeric:tabular-nums}
.bartrack{min-width:0}
.visitors-summary18{padding:var(--frame-padding18)}
@media(max-width:850px){.info-grid,.figuregrid,.coverage-grid,.evidence-grid{grid-template-columns:1fr}.info-grid>.card:last-child{grid-column:auto}.metricgrid{grid-template-columns:repeat(2,minmax(0,1fr))}.barrow{grid-template-columns:minmax(140px,35%) minmax(0,1fr) 85px}}
@media(max-width:550px){:root{--frame-padding18:16px;--frame-gap18:16px}.tablewrap th,.tablewrap td,.tablewrap .compact th,.tablewrap .compact td,.tablewrap caption{padding:12px}.metricgrid{gap:12px}.metricgrid>div{padding:12px}.kv{grid-template-columns:minmax(100px,40%) minmax(0,1fr);gap:8px 12px}.barrow{grid-template-columns:minmax(0,1fr) 85px}.barrow .label{grid-column:1/-1}.barrow .bartrack{grid-column:1}.barrow>span:last-child{grid-column:2}.m14-stats{grid-template-columns:repeat(2,minmax(0,1fr))}}

.variant-browser-table18 th:nth-child(5),.variant-browser-table18 td:nth-child(5){text-align:right}
.variant-browser-table18 th:nth-child(6),.variant-browser-table18 td:nth-child(6){text-align:left}

.country-outcomes19{table-layout:fixed;min-width:760px}
.country-outcomes19 th:first-child{width:34%}
.country-outcomes19 th:not(:first-child),.country-outcomes19 td:not(:first-child){text-align:right;font-variant-numeric:tabular-nums}

/* Compact Variant browser with wrapped headings and cells. */
#workspace .variant-browser-table18{width:100%;min-width:0;table-layout:fixed}
#workspace .variant-browser-table18 th,#workspace .variant-browser-table18 td{padding:12px 8px;white-space:normal;overflow-wrap:anywhere;word-break:normal}
#workspace .variant-browser-table18 th{font-size:10px;letter-spacing:.3px;line-height:1.5;vertical-align:bottom}
#workspace .variant-browser-table18 .table-sort18{display:flex;flex-direction:column;align-items:stretch;gap:5px;width:100%;white-space:normal}
#workspace .variant-browser-table18 .table-sort-label18{white-space:normal;overflow-wrap:normal;word-break:normal}
#workspace .variant-browser-table18 .table-sort-icon18{align-self:flex-end}
#workspace .variant-browser-table18 .pill{white-space:normal;overflow-wrap:anywhere}
#workspace .variant-browser-table18 .subnote{white-space:normal;overflow-wrap:anywhere}
@media(max-width:700px){#workspace .variant-browser-table18 th,#workspace .variant-browser-table18 td{padding:8px 3px;font-size:10px}#workspace .variant-browser-table18 th{font-size:8px}#workspace .variant-browser-table18 .table-sort-label18{overflow-wrap:anywhere}}

#workspace th[aria-sort]{vertical-align:middle}
#workspace .table-sort18{display:inline-flex;align-items:center;justify-content:inherit;gap:6px;max-width:100%;margin:0;padding:0;border:0;border-radius:2px;background:transparent;color:inherit;font:inherit;letter-spacing:inherit;text-transform:inherit;text-align:inherit;line-height:inherit;cursor:pointer}
.table-sort-label18{min-width:0;overflow-wrap:anywhere}
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#workspace th[aria-sort="ascending"],#workspace th[aria-sort="descending"]{color:#176c94;background:#e4eff5}
#workspace th[aria-sort="ascending"] .table-sort-icon18,#workspace th[aria-sort="descending"] .table-sort-icon18{color:#176c94}
#workspace .table-sort18:hover{color:#176c94;background:transparent}
#workspace .table-sort18:focus-visible{outline:2px solid #176c94;outline-offset:4px}
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.offline-note17{padding:9px 14px;background:#eaf2f7;color:#274756;font:13px Arial,sans-serif;border-bottom:1px solid #ccd9e2} .offline-note17 a{color:#176c94}